Our lab studies environmentally-switched protein/protein interaction domains about their natural regulation and understand how to artificially control them in vitro and in living cells. This is exemplified by our work on photosensors, parts of the hypoxia response, and others.

April 2018: Welcome to new lab members Roksana Asad, Matt Cleere and Xingjian Xu, joining us at the Structural Biology Initiative of the CUNY Advanced Science Research Center. Kevin directs this new initiative, which will catalyze collaborations among biological and physical scientists in the ASRC and elsewhere in the CUNY system.

Please find me by email with any questions or comments - Kevin Gardner kglab.org

for July 19, 2019, as found in VP Denisov et al., Nat. Struct. Biol. 3(1996): 505:

"While the Arrhenius equation is still widely used to analyse temperature dependent protein conformational dynamics, the two-state picture on which it rests can hardly do justice to the complex topography of the energy landscape of a protein, even on a local scale."