Our lab studies environmentally-switched protein/protein interaction domains about their natural regulation and understand how to artificially control them in vitro and in living cells. This is exemplified by our work on photosensors, parts of the hypoxia response, and others.

April 2018: Welcome to new lab members Roksana Asad, Matt Cleere and Xingjian Xu, joining us at the Structural Biology Initiative of the CUNY Advanced Science Research Center. Kevin directs this new initiative, which will catalyze collaborations among biological and physical scientists in the ASRC and elsewhere in the CUNY system.

Please find me by email with any questions or comments - Kevin Gardner kglab.org

for May 21, 2019, as found in MA Young et al., Cell 105(2001): 115:

"The activation loops remain close to the starting conformation throughout the simulations, showing no tendency to flip out."