Our lab studies environmentally-switched protein/protein interaction domains about their natural regulation and understand how to artificially control them in vitro and in living cells. This is exemplified by our work on photosensors, parts of the hypoxia response, and others.

Feb 2020: The website is being refreshed after a bit too long! Take a look here to learn a bit more about our work at the Structural Biology Initiative of the CUNY Advanced Science Research Center. Kevin directs this initiative, which catalyzes collaborations among biological and physical scientists in the ASRC and elsewhere in the CUNY system.

Find me on Twitter or email with questions or comments - Kevin Gardner kglab.org

for May 24, 2020, as found in J Kuriyan, Cell 116(2004): 356:

"In our quest to understand how proteins work, things would be much easier if protein domains were rigid and simply did whatever it is that they are supposed to do without jiggling around too much."